You can set up a coupon to work for a certain number of times, for a specific time frame, but the only way you could make it only work once, for 1 user would be to give them an individual code (which of course would be a real hassel). So, at this time, no it's not possible with the current version (unless you made customizations of your own to enable this to happen).
The
ClassiPress Admin Demo shows exactly what you can set in terms of the specific coupons.